SPRAVATO™
A nasal spray taken in our office with about two hours of rest and monitoring. Often used together with an oral antidepressant.
About SPRAVATO™Depression treatment in Las Vegas
When antidepressants aren’t working, you still have options
If you’ve tried two or more antidepressants and still don’t feel like yourself, it isn’t your fault, and it isn’t the end of the road. Calm Clinic offers three advanced treatments that work differently from daily pills.
Compare your options
A quick side-by-side. Your provider will help you choose based on your history and goals.
| Feature | SPRAVATO™ | TMS Therapy | Ketamine Assisted Therapy |
|---|---|---|---|
| What it is | Esketamine nasal spray | Magnetic pulses to mood-regulating areas of the brain | Ketamine (sublingual or injection) paired with psychotherapy |
| FDA status | FDA-approved for treatment-resistant depression | FDA-cleared for depression and OCD | Off-label use for depression |
| Visit length | About 2 hours (includes monitoring) | As little as 20 minutes | About 2–3 hours |
| Typical schedule | 2× a week for a month, then weekly or every other week | 5 days a week for 4–6 weeks, then a taper | A series of sessions with preparation and integration therapy |
| Drive yourself? | No, arrange a ride | Yes | No, arrange a ride |
| Insurance | Covered by many plans, incl. Medicare | Covered by many plans, incl. Medicare | Generally self-pay; therapy visits may be covered |
| Good fit if… | You prefer fewer visits per week | You want to avoid medication side effects | You want a deeper, therapy-centered experience |
Coverage depends on your specific plan and eligibility. We verify benefits before you begin.
TMS Therapy
Non-invasive, medication-free sessions as short as 20 minutes. Drive yourself and get right back to your day.
About TMSKetamine Assisted Therapy
Ketamine paired with preparation and integration psychotherapy, guided by providers who specialize in this work. Offered only after a full psychiatric evaluation.
About KAPNot sure where to start?
That’s what the first visit is for. We’ll review what you’ve tried, check your insurance, and recommend the option that fits your life.
Frequently asked questions
What counts as treatment-resistant depression?
Treatment-resistant depression generally describes major depressive disorder that has not responded adequately to at least two different antidepressants taken at an adequate dose and for an adequate length of time.
Should I try SPRAVATO™ or TMS first?
It depends on your health history, schedule, insurance, and preferences. TMS has no medication side effects and you can drive yourself, but it requires daily visits for several weeks. SPRAVATO™ needs fewer visits per week, but you’ll need a ride home each time. Your provider will help you decide, and if one isn’t a fit, the other may be.
Do I need a referral?
No. Referrals are not required. You can request an appointment directly, and we’re also happy to work with your current psychiatrist or primary care provider.